Lp(a): the inherited cholesterol number most people have never checked

What is Lp(a)?

Lp(a) is a particle similar to LDL (bad) cholesterol. Your level is mostly determined by your genes and stays about the same throughout life. Diet and exercise do not change it much.

Why it matters

A high Lp(a) level raises the risk of heart attack, stroke and narrowing of the aortic valve, even when other cholesterol numbers look normal. About 1 in 5 people have a high level.

Who should be tested

The 2026 ACC/AHA cholesterol guideline recommends measuring Lp(a) at least once in all adults. It is especially important if you have a family history of early heart disease or stroke.

What if my level is high?

Your doctor will focus on lowering your other risks: LDL cholesterol, blood pressure, blood sugar and smoking. A high Lp(a) can also affect decisions about cholesterol medication. Since it runs in families, your relatives may want to be tested too.

Check your coverage

Some insurance plans do not cover Lp(a) as a preventive test. Please check with your plan.

This article is for general education and does not replace a visit with your doctor.